We’re super excited about the Statistical Assessment of Modeling of Proteins and Ligand (SAMPL) series of blind challenges, and the potential these have for driving real advancements in modeling in our field. These challenges not only provide an opportunity for blind, prospective testing of our methods, but they also provide a crowdsourcing model to drive innovation. Such approaches have a well-documented history of spurring progress in specific areas, such as in the XPrize, the Netflix Prize, or, closer to our field, the DREAM challenges or CASP for protein structure prediction.
In any case, we’re seeking funding to continue these challenges, so, as part of the process of revising our proposal (original SAMPL proposal here), we surveyed the SAMPL community, and I’m excited to report that the results of our SAMPL survey are out! Folks were very enthusiastic about our plans, but also gave us some great feedback we’re incorporating to make SAMPL even more valuable.